Gastric Bypass Surgery Risks: It Leads To Colorectal Cancer According To New Study

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Gastric Bypass Surgery Risks: It Leads To Colorectal Cancer According To New Study and Roux-en-Y Gastric Bypass Surgery Risks –and raised further over time, reported Dr. Maryam Derogar, of the Karolinska Institute, Stockholm, and her links.

The risk of colorectal cancer mostly arose between people who had undergone obesity surgery in a retrospective cohort study of more than 77,000 obese patients enrolled in a Swedish registry.   No such formula overtime was seen among the fat patients who did not have Gastric Bypass Surgery Risks.”Our arranged data suggest that accessed colorectal cancer risk may be a long-term consequence of such Gastric Bypass Surgery Risks,” they concluded.

If the association is confirmed, they added, “it should stimulate research addressing colonoscopic evaluation of the incidence of colorectal adenomatous polyps after obesity surgery with a view to defining an optimum colonoscopy surveillance strategy for the increasing number of patients who undergo obesity surgery.

Gastric Bypass Surgery Risks To address their “unexpected” finding in an earlier study of an apparent increase in the risk of colorectal cancer after obesity surgery, but no increase in the risk of other cancers related to obesity, they conducted a retrospective cohort study using national registry data between 1980 and 2016, of 15,095 obese patients who had undergone obesity surgery and 62,016 patients who had been diagnosed with obesity but did not undergo surgery

Gastric Bypass Surgery Risks: It Leads To Colorectal Cancer According To New Study

They calculated the colorectal cancer risk using the standardized incidence ratio (SIR), the observed number of cases divided by the number of expected cases in that group.Over a median of 10 years, there were 70 colorectal cancers in the obesity surgery group; and over a median of 7 years, 373 among those who had no surgery.

The SIR for colorectal cancer among those who had surgery was 1.60, which was statistically significant. GastricBypass Surgery Risks Among those who had no surgery, there was a small, insignificant increase in risk group (a SIR of 1.26). In the surgery group, the risk increased over time in men and women, up to a twofold increased risk among those patients followed for at least 10 years, a pattern than was not observed in the obese patients who had no surgery.


View on the News of gastric bypass surgery risks: 

There are several reports that show a protective effect of bariatric GastricBypass Surgery Risks on future cancer risk. This report by Derogar and colleagues, published in Annals of Surgery, is the first to suggest that bariatric surgery is associated with an increased risk of colorectal cancer over time.

The authors suggest a possible mechanism that may be related to an increase in putative mucosal biomarkers of colorectal cancer and Gastric Bypass Surgery Risks risk and mucosal proinflammatory gene expression following Roux-en-Y gastric bypass. Also, a high-protein diet can promote detrimental metabolic profiles promoting carcinogenesis in the colon and rectum.

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